A T&M Freightliner tractor trailer overturned on Interstate 26 near mile marker 11 just before noon, causing the right side of the eastbound lanes to be closed.
According to a Johnson City Police Department crash report, Phillip Edward Young, 54, of Lake City, S.C., ran off the road, hit a guardrail and overturned.
Young was taken to the Johnson City Medical Center for treatment.
No information was available about the contents of the trailer.